General Information
NameProf. Joseph Kost
DepartmentDepartment of Chemical Engineering
Emailkost@bgu.ac.il
Personal Web SitePersonal Web Site
Academic RankProfessor


Books

 
[1] Kost J., Liu, L, Kost, J. Fishman, M. and Hicks, K. “A Review: Controlled Release Systems for Agricultural and Food Applications” in New Delivery Systems for the Controlled Drug Release from Naturally Occurring Materials, by N. Parris, L. S. Liu, C. Song and V. P. Shastri (Eds.): ACS Symposiuim Series 992, 2008, p.265-281. (2008).

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Book Chapters

 
[1] Kost J., Ultrasound in Percutaneous Absorption", in: Enhancement in Drug Delivery, CRC press, 317-330, (2006).

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Journal Articles

 
[1] Traitel T., Goldbart R., Kost J., Smart polymers for responsive drug-delivery systems, Journal of Biomaterials Science, Polymer Edition, 19, 6, 755 - 767, (2008).
[2] Tali Katav, Liu Linshu, Tamar Traitel, Riki Goldbart, Kost J., Modified pectin-based carrier for gene delivery: cellular barriers in gene delivery course, Journal of Controlled Release, 130, 183-191, (2008).
[3] Lavon I., Grossman N., Kost J., Kimmel E., Bubble growth within the skin by rectified diffusion might play a significant role in sonophoresis. Journal of Controlled Release, 117, 246-255, (2007).
[4] Kost J., Controlling Liposomal Drug Release by Low-Frequency Ultrasound: Mechanism and Feasibility, Langmuir, 23, 4019-4025, (2007).
[5] Acharya S., Patla I., Kost J., Efrima S., Golan Y., Switchable assembly of ultra narrow CdS nanowires and nanorods, Journal of the American Chemical Society, 128, 29, 9294-9295, (2006).
[6] Aschkenasy C., Kost J., On-demand release by ultrasound from osmotically swollen hydrophobic matrices, Journal of Controlled Release, 110, 1, 58-66, (2005).
[7] Eliaz R., Kost J., Applications of injectable polymeric implants for protein and DNA delivery, Israel Journal of Chemistry, 45, 4, 437-444, (2005).
[8] Lavon I., Grossman N., Kost J., The nature of ultrasound-SLS synergism during enhanced transdermal transport, Journal of Controlled Release, 107, 3, 484-494, (2005).
[9] Kost J., Naim B., Traitel T., Sieradzki R., Geresh S., Reich Z., Polysaccharide carriers for non-viral gene delivery applications. Abstracts of Papers of the American Chemical Society, 228, U49-U49, (2004).
[10] Lavon A., Kost J., Ultrasound and transdermal drug delivery, Drug Discovery Today, 9, 15, 670-676, (2004).
[11] Geresh S., Gdalevsky G., Gilboa I., Voorspoels J., Remon J., Kost J., Bioadhesive grafted starch copolymers as platforms for peroral drug delivery: a study of theophylline release, Journal of Controlled Release, 94, 2-3, 391-399, (2004).
[12] Mitragotri S., Kost J., Low-frequency sonophoresis: A review, Advanced Drug Delivery Reviews, 56, 5, 589 - 601, (2004).
[13] Traitel T., Kost J., pH-responsive hydrogels: swelling model. Advances in experimental medicine and biology, 553, 43, (2004).
[14] Katz N., Shapiro ., Herrmann ., Kost J., Custer ., Rapid onset of cutaneous anesthesia with EMLA cream after pretreatment with a new ultrasound-emitting device. Anesthesia and analgesia, 98, 2, 6, table of contents, (2004).
[15] Traitel T., Kost J., Lapidot ., Modeling ionic hydrogels swelling: characterization of the non-steady state. Biotechnology and bioengineering, 84, 1, 8, (2003).
[16] Liu L., Fishman ., Kost J., Hicks ., Pectin-based systems for colon-specific drug delivery via oral route. Biomaterials, 24, 19, 43, (2003).
[17] Goldbart R., Traitel T., Lapidot S., Kost J., Enzymatically controlled responsive drug delivery systems, Polymers for Advanced Technologies, 13, 10-12, 1006-1018, (2002).
[18] Geresh S., Gilboa Y., Peisahov-Korol J., Gdalevsky G., Voorspoels J., Kost J., Remon J.P., Preparation and characterization of bioadhesive grafted starch copolymers as platforms for controlled drug delivery, Journal of Applied Polymer Science, 86, 5, 1157-1162, (2002).
[19] Terahara T., Mitragotri S., Kost J., Langer R., Dependence of low-frequency sonophoresis on ultrasound parameters; distance of the horn and intensity, International Journal of Pharmaceutics, 235, 1-2, 35-42, (2002).
[20] Kost J., Ultrasound-assisted insulin delivery and noninvasive glucose sensing. Diabetes technology & therapeutics, 4, 4, 97, (2002).
[21] Mitragotri S., Kost J., Transdermal delivery of heparin and low-molecular weight heparin using low-frequency ultrasound, pharmaceutical research, 18, 8, 1151-1156, (2001).
[22] Kost J., Langer R., Responsive polymeric delivery systems, Advanced Drug Delivery Reviews, 46, 1-3, 125-148, (2001).
[23] Eliaz R., Wallach D., Kost J., Delivery of soluble tumor necrosis factor receptor from in-situ forming PLGA implants: In-vivo, pharmaceutical research, 17, 12, 1546-1550, (2000).
[24] Le L., Kost J., Mitragotri S., Combined effect of low-frequency ultrasound and iontophoresis: Applications for transdermal heparin delivery, pharmaceutical research, 17, 9, 1151-1154, (2000).
[25] Mitragotri S., Coleman M., Kost J., Langer R., Analysis of ultrasonically extracted interstitial fluid as a predictor of blood glucose levels, Journal of Applied Physiology, 89, 3, 961-966, (2000).
[26] Mitragotri S., Ray D., Farrell J., Tang H., Yu B., Kost J., Blankschtein D., Langer R., Synergistic effect of low-frequency ultrasound and sodium lauryl sulfate on transdermal transport, Journal of Pharmaceutical Sciences, 89, 7, 892-900, (2000).
[27] Traitel T., Cohen Y., Kost J., Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions, Biomaterials, 21, 16, 1679-1687, (2000).
[28] Mitragotri S., Coleman M., Kost J., Langer R., Transdermal extraction of analytes using low-frequency ultrasound, pharmaceutical research, 17, 4, 466-470, (2000).
[29] Eliaz R., Kost J., Characterization of a polymeric PLGA-injectable implant delivery system for the controlled release of proteins, Journal of Biomedical Materials Research, 50, 3, 388-396, (2000).
[30] Kost J., Langer R., Responsive polymeric delivery systems, Advanced Drug Delivery Reviews, 46, 1-3, 125 - 148, (2000).
[31] Mitragotri S., Kost J., Low-frequency sonophoresis: a noninvasive method of drug delivery and diagnostics, Biotechnology Progress, 16, 3, 488 - 492, (2000).
[32] Kost J., Mitragotri S., Gabbay ., Pishko ., Transdermal monitoring of glucose and other analytes using ultrasound. Nature medicine, 6, 3, 50, (2000).
[33] Mitragotri S., Farrell ., Tang ., Terahara ., Kost J., Determination of threshold energy dose for ultrasound-induced transdermal drug transport. Journal of controlled release : official journal of the Controlled Release Society, 63, 1-2, 52, (2000).
[34] Goldbart R., Kost J., Calcium responsive bioerodible drug delivery system, pharmaceutical research, 16, 9, 1483-1486, (1999).
[35] Kost J., Goldbart R., Calcium responsive drug delivery systems based on polysaccharides. Abstracts of Papers of the American Chemical Society, 217, U561-U561, (1999).
[36] Eliaz R., Grossman N., Katz S., Zur-Mashiach R., Grunwald M., Reuveni H., Rosenberg L., Kost J., In vitro analysis of bromine chemical burns with use of full-thickness human skin, journal of burn care & rehabilitation, 19, 1, 18-24, (1998).
[37] Lavon I., Kost J., Mass transport enhancement by ultrasound in non-degradable polymeric controlled release systems, Journal of Controlled Release, 54, 1, 1-7, (1998).
[38] Schwartz M., Guterman ., Kost J., Electrical properties of glucose-sensitive hydrogels: swelling and conductivity relationships. Journal of biomedical materials research, 41, 1, 70, (1998).
[39] Machluf M., Peled Y., Kost J., Characterization of microencapsulated liposome systems for the controlled delivery of liposome-associated macromolecules, Journal of Controlled Release, 43, 1, 35-45, (1997).
[40] Band M., Gutman M., Faerman V., Korngold E., Kost J., Plath P.J., Gontar V., Influence of specially modulated ultrasound on the water desalination process with ion-exchange hollow fibers, Desalination, 109, 3, 303 - 313, (1997).
[41] Eliaz R., Wallach D., Kost J., Long-term protection against the effects of tumor necrosis factor by controlled delivery of the soluble p55 TNF receptor, Cytokine, 8, 6, 482-487, (1996).
[42] Kost J., Pliquett U., Mitragotri S., Yamamoto A., Langer R., Weaver J., Synergistic effect of electric field and ultrasound on transdermal transport, Pharmaceutical research, 13, 4, 633-638, (1996).
[43] Kost J., Liu L., Gabelnick H., Langer R., Ultrasound As A Potential Trigger To Terminate the Activity of Contraceptive Delivery Implants, Journal of Controlled Release, 30, 1, 77-81, (1994).
[44] Kost J., Liu L., Ferreira J., Langer R., Enhanced protein blotting from PhastGel media to membranes by irradiation of low-intensity ultrasound, Analytical Biochemistry, 216, 1, 27-32, (1994).
[45] Kost J., Biosensors based on intelligent polymeric systems, Artificial Cells, Blood Substitutes, and Immobilization Biotechnology, 22, 5, 25 -, (1994).
[46] Kost J., Foux A., Narkis M., Quantitative model relating electrical resistance, strain, and time for carbon black loaded silicone rubber, Polymer Engineering and Science, 34, 21, 1628 - 1634, (1994).
[47] Machluf M., Kost J., Ultrasonically Enhanced Transdermal Drug-delivery - Experimental Approaches To Elucidate the Mechanism, journal of biomaterials science polymer edition, 5, 1-2, 147-156, (1993).
[48] Kost J., Ultrasound induced delivery of peptides, Journal of Controlled Release, 24, 1-3, 247-255, (1993).
[49] Goldraich M., Kost J., Glucose-sensitive polymeric matrices for controlled drug delivery, Clinical Materials, 13, 1-4, 135 - 142, (1993).
[50] Kost J., Ultrasound for controlled delivery of therapeutics, Clinical Materials, 13, 1-4, 155 - 161, (1993).
[51] Kost J., Langer R., Responsive polymer systems for controlled delivery of therapeutics, trends in biotechnology, 10, 4, 127-131, (1992).
[52] Kost J., Goldraich M., Glucose responsive hydrogels for medical applications, Abstracts of Papers of the American Chemical Society, 203, 113-PMSE, (1992).
[53] Liu L.-S., Kost J., D'Emanuele A., Langer R., Experimental approach to elucidate the mechanism of ultrasound-enhanced polymer erosion and release of incorporated substances, Macromolecules, 25, 1, 123-128, (1992).
[54] Shefer A., Shefer S., Kost J., Langer R., Structural characterization of starch networks in the solid state by cross-polarization magic-angle-spinning 13C NMR spectroscopy and wide angle X-ray diffraction, Macromolecules, 25, 25, 6756 - 6760, (1992).
[55] D'Emanuele A., Kost J., Hill J., Langer R., Investigation of the effects of ultrasound on degradable polyanhydride matrices, Macromolecules, 25, 2, 511 - 515, (1992).
[56] Kost J., Langer R., Responsive polymeric delivery systems, Advanced Drug Delivery Reviews, 6, 1, 19 - 50, (1991).
[57] Langer R., Kost J., Real time response polymeric delivery systems, Annals of the New York Academy of Sciences, 618, 330 -, (1991).
[58] Kost J., Shefer S., Chemically-modified Starches for Targeted Drug Delivery, Abstracts of Papers of the American Chemical Society, 200, 11-PMSE, (1990).
[59] Kost J., Shefer S., Natural Polysaccharides for Enzymatically Controlled Drug Delivery, Abstracts of Papers of the American Chemical Society, 199, 1, 121-POLY, (1990).
[60] Siegel R., Kost J., Langer R., Mechanistic Studies of Macromolecular Drug Release From Macroporous Polymers .1. Experiments and Preliminary Theory Concerning Completeness of Drug Release, Journal of Controlled Release, 8, 3, 223-236, (1989).
[61] Levy D., Kost J., Meshulam ., Effect of ultrasound on transdermal drug delivery to rats and guinea pigs. The Journal of clinical investigation, 83, 6, 8, (1989).
[62] Kost J., Leong K., Langer R., Ultrasonically controlled polymeric drug delivery, Makromolekulare Chemie Macromolecular Symposia, 19, 275-285, (1988).
[63] Kost J., Polymeric controlled drug delivery systems, Israel Journal of Technology, 24, 3-4,Pt B, 653 - 660, (1988).
[64] Kost J., Wolfrum J., Langer R., Magnetically enhanced insulin release in diabetic rats. Journal of Biomedical Materials Research, 21, 12, 1367 - 1373, (1987).
[65] Leong K., Kost J., Mathiowitz E., Langer R., Polyanhydrides for controlled release of bioactive agents, Biomaterials, 7, 5, 364-371, (1986).
[66] Kost J., Langer R., Advances in Drug Delivery - Magnetically Modulated Drug Delivery Systems, Pharmacy International, 7, 3, 60-63, (1986).
[67] Langer R., Kost J., Fischelghodsian F., Brown L., Leong K., Regulation of Controlled Release by Ultrasound or Enzyme, Abstracts of Papers of the American Chemical Society, 191, 47-INDE, (1986).
[68] Langer R., Siegel R., Brown L., Leong K., Kost J., Edelman E., Controlled Release - 3 Mechanisms, Chemtech, 16, 2, 108-110, (1986).
[69] Langer R., Siegel R., Brown L., Leong K., Kost J., Edelman E., Controlled Release: Three Mechanisms. Chemtech, 16, 2, 108 - 110, (1986).
[70] Langer R., Siegel R., Brown L., Leong K., Kost J., Edelman E., Controlled release and magnetically modulated systems for macromolecular drugs, Annals of the New York Academy of Sciences, 446, 1-13, (1985).
[71] Kost J., Noecker R., Kunica E., Langer R., Magnetically Controlled Release Systems - Effect of Polymer Composition, Journal of Biomedical Materials Research, 19, 8, 935-940, (1985).
[72] Kost J., Noecker R., Kunica E., Langer R., Magnetically controlled release systems: effect of polymer composition. Journal of Biomedical Materials Research, 19, 8, 935 - 940, (1985).
[73] Kost J., Horbett T., Ratner B., Singh M., Glucose-sensitive membranes containing glucose oxidase: activity, swelling, and permeability studies. Journal of Biomedical Materials Research, 19, 9, 1117 - 1133, (1985).
[74] Edelman E. R., Kost J., Bobeck H., Langer R., Regulation of Drug Release From Polymer Matrices by Oscillating Magnetic Fields. Journal of Biomedical Materials Research, 19, 1, 67 - 83, (1985).
[75] Kost J., Langer R., Controlled release of bioactive agents, trends in biotechnology, 2, 2, 47-51, (1984).
[76] Langer R., Siegel R., Brown L., Leong K., Kost J., Edelman E., Controlled Release Systems - Some Recent Advances, Abstracts of Papers of the American Chemical Society, 188, AUG, 23-PMSE, (1984).
[77] Edelman E., Brown ., Kost J., Taylor ., Modulated release from polymeric drug delivery systems using oscillating magnetic fields: in vitro and in vivo characteristics. Transactions - American Society for Artificial Internal Organs, 30, 9, (1984).
[78] Kost J., Narkis M., Foux A., Resistivity Behavior of Carbon-black-filled Silicone Rubber in Cyclic Loading Experiments. Journal of Applied Polymer Science, 29, 12 pt 1, 3937 - 3946, (1984).
[79] Brown L., Munoz C., Siemer L., Edelman E., Kost J., Langer R., Sustained Insulin Release from Implantable Polymers, diabetes, 32, A35-A35, (1983).
[80] Horbett T., Kost J., Ratner B., Swelling behavior of glucose sensitive membranes, Abstracts of Papers of the American Chemical Society, 185, MAR, 86-POLY, (1983).
[81] Kost J., Narkis M., Foux A., Effects of axial stretching on the resistivity of carbon black filled silicone rubber, Polym. Eng. Sci. (USA), 23, 10, 567 - 71, (1983).
[82] Gutman D., Minkov B., Kost J., Benaryeh H., the Quantitative Measurement of Occlusion by Photoplasticity, Actualites Odonto-stomatologiques, 138, 273-280, (1982).
[83] Siegmann A., Narkis M., Kost J., Dibenedetto A., Mechanism of low profile behavior in unsaturated polyester systems, International Journal of Polymeric Materials, 6, 3-4, 217-231, (1978).

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Conference Proceedings

 
[1] Kost J., Breaking the Skin Barrier; No Pain, More Gain. (invited lecture). Emerging Trin Pharmaceutical Sciencesends, U.P. Technical University, (2006).
[2] Langer R., Siegel R., Brown L., Leong K., Kost J., Edelman E., Controlled Release Systems: Some Recent Advances. Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Material,Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Material, 115 - 118, (1984).
[3] Horbett T., Kost J., Ratner B., Swelling behavior of glucose sensitive membranes. 193 - 207, (1984).
[4] Kost J., Edelman E., Brown L., Langer R., Magnetically Modulated Release From Implantable Devices. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium,Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, 340 -, (1984).
[5] Horbett T., Kost J., Coleman D., Ratner B., Glucose Sensitive Membranes: Stability and Biocompatibility Studies. Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium,Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, 341 -, (1984).
[6] Edelman E. R., Linhardt R. J., Bobeck H., Kost J., Rosen H. B., Langer R., Polymer Based Drug Delivery: Magnetically Modulated and Bioerodible Systems. 279 - 292, (1984).
[7] Horbett T., Kost J., Ratner B., Swelling behavior of glucose sensitive membranes. Polymer Preprints, Division of Polymer Chemistry, American Chemical Society,Polymer Preprints, Division of Polymer Chemistry, American Chemical Society, 34 - 35, (1983).

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Poster

 
[1] Lavon I, Kimmel E, Kost J., "A Mathematical Model of Sonophoresis by Rectified Diffusion", 33rd Annual Meeting of the Controlled Release Society, Vienna, Austria, (2006).

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